David L. Glanzman

Behavioral Neuroscience: No Easy Path from Genes to Cognition

Two recent studies illustrate the limits of a strictly molecular approach toward understanding learning and memory.

Synaptic Facilitation and Behavioral Dishabituation in Aplysia: Dependence on Release of Ca from Postsynaptic Intracellular Stores, Postsynaptic Exocytosis, and Modulation of Postsynaptic AMPA Receptor Efficacy

Quan Li,1* Adam C. Roberts,2* and David L. Glanzman1,3 1Department of Physiological Science and 2Interdepartmental PhD Program in Molecular, Cellular, and Integrative Physiology, University of California Los Angeles, Los Angeles, California 90095-1606, and 3Department of Neurobiology and Brain Research Institute, David Geffen School of Medicine at University of California Los Angeles, Los Angel...

UCLA UCLA Electronic Theses and Dissertations Title

Octopus Conditioning: A Multi-Armed Approach to the LTP–Learning Question

A recent study shows that avoidance conditioning in the cephalopod Octopus vulgaris is mediated by long-term potentiation (LTP), a form of synaptic plasticity thought to be important in vertebrate associative learning. Thus, LTP appears to be an evolutionarily conserved learning mechanism.

Simple Minds: The Neurobiology of Invertebrate Learning and Memory

ALTHOUGH IT HAS BEEN FORMALLY RECOGNIZED since the end of the 19th century that invertebrates can learn (Romanes 1895), the modern neurobiological analysis of invertebrate learning did not begin until the 1960s. Starting in that decade, pioneering investigators began to use intracellular electrophysiology to probe the basic mechanisms of learning in higher invertebrates (Bruner and Tauc 1966; K...